What hope is there for this diabetic foot?
My grandmother is 65 and has diabetes. Her foot looks very similar to this picture (although it is on this inside of her foot, not on the bottom).
http://www.aafp.org/afp/20021101/1655_f1.jpg
The hole leaks fluids daily. She can not walk without her specially made cast (because the bone in her foot is deformed). She is always experiencing leg pains.
Doctors have tried various things for years...
Do you think there is hope that the wound will heal? Is there a chance that her foot will recover?
Thank you so much for your honest imput. 
I don't know what treatments she has had.But this is the last resort. And maybe the best treatment.
A 79-year-old man with type 2 diabetes mellitus developed heel and forefoot ulcers, for which he received currently recommended therapy, (1-5) including an off-loading orthotic, systemic antibiotics selected by infectious disease consultants, and topical therapies directed by a wound care expert.
After 14 months of care costing more than $390,000--which was the cost of 5 hospitalizations and 4 surgeries--the ulcers measured 8 x 5 cm and 3 x 3 cm. Deep tissue cultures grew methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and Pseudomonas.
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During this time the patient lost 2 toes but refused below-the-knee amputation. He was informed by 2 different surgical teams that without this surgery he would likely die. This opinion was based on the patient's recurrent episodes of heel osteomyelitis and multiple medical complications, including acute renal failure from culture-specific antibiotics.
The patient was eventually discharged to his home at his request, after consulting with his family and the hospital's ethics committee. He lost a third toe before consenting to a trial of topical honey.
* Course of treatment with honey
Once-daily, thick applications of ordinary honey purchased at a supermarket were smeared on gauze 4x4s and placed on the wounds, which were then wrapped. Oral antibiotics and saline dressings were discontinued, but otherwise treatment was unchanged. Since the patient's family purchased and applied the honey, the cost of this therapy was merely that of the dressings. Dressing changes were painless and the serum glucose remained in excellent control.
Granulation tissue appeared within 2 weeks; in 6 to 12 months the ulcers resolved (see FIGURES 1-6). Two years later, the ulcers have not recurred; the patient ambulates with a walker and reports improved quality-of-life.
[FIGURES 1-6 OMITTED]
* Honey as wound treatment in the medical literature
Honey has been used to treat wounds for millennia, (6) but the medical evidence supporting its use is limited. While there are many case reports of honey's effectiveness, (7) controlled trials demonstrating effectiveness for treating burns and wounds are limited by poor quality and the use of nonstandard controls, (7) while another trial found minimal benefit when "a very thin smear" was used. (8) Concerns about wound infection from Clostridium spores (9) appear unfounded, as no such complication has been described in more than 500 reports in the literature, (10) and honey has repeatedly been shown to suppress bacterial growth. (11)
Gamma-irradiated "medical" honey is available, which has also been selected for its potent antibacterial properties, although most of the cases in the medical literature have used raw honey. A burning or stinging sensation has been described with honey's topical use.
As rates of diabetes increase, it is important to identify effective strategies to reduce amputation rates, both to improve quality of life (12) and to decrease cost. (13) Given honey's potential for improved outcomes, cost savings, and decreasing antibiotic use and resistance, we advocate publicly funded randomized controlled trials to determine its efficacy. Meanwhile, we encourage others to consider topical honey therapy for patients with refractory diabetic foot ulcers.
Also go to the webs sites if you type in (Using Honey for foot ulcers)
Good luck to grandma.
Telemedicine
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